BioHub Maryland®

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Early Vaccines & Immunotherapies Interns

Company AstraZeneca
Job Location Gaithersburg, MD
Salary Range $80–$120k
Time Type Full Time
Seniority Mid Level
Posted December 2, 2025
Application Deadline December 17, 2025

We are looking Undergraduate, Master’s, and PhD-level students majoring in Biology, Microbiology, Biomedical Engineering, Biochemistry, Biotechnology or related field for 12-week internship role in Gaithersburg, MD from May 18 2026 to August 7 2026.

The below intern projects are positioned for this Summer:

Anti-microbial Single Domain Antibodies; from Technology Development to Drug Discovery Graduate-Level Project

  • Work with scientists/senior scientists in group to develop new methods for antiviral and antibacterial single domain antibody discovery
  • Utilize wet lab skills to characterize potential lead molecules for antiviral and antibacterial programs
  • Present findings in departmental meetings

Automated High Throughput Enzyme Engineering to Improve Bioconjugate Vaccine Production Graduate-Level Project

  • Implement and optimize an automated high throughput enzyme engineering workflow including colony picking, expression, lysis, and analytical readout
  • Analyze growth and expression data to guide hit selection for the next round of screening
  • Summarize the data and present to stakeholders

Virology Bioassay & Automation Undergraduate-Level Project

  • Culture and maintain multiple mammalian cell lines under sterile conditions.
  • Perform in vitro cell-based bioassays, including infection-based assays and reporter or endpoint-based readouts.
  • Support the development, optimization, and qualification of assays evaluating immune responses to vaccine candidates and/or the antiviral potency and neutralization activity of mAbs against respiratory or chronic viral targets.
  • Utilize laboratory automation systems (e.g., liquid handlers, high-throughput plate readers, automated incubators) to execute cell-based workflows.
  • Analyze and interpret experimental data; prepare data summaries, figures, and a final presentation to the team.

Assessing Human Immunological Responses to a Novel Vaccine Undergraduate-Level Project

  • Conduct in vitro cell stimulation and culture assays to assess cellular immunity following vaccination.
  • Analyze and interpret immunological data to connect results to study objectives.
  • Generate regular written reports and presentations to effectively communicate results to broader study team.

Position Requirements:

  • Undergraduate, Master’s, and PhD-level students majoring in Biology, Microbiology, Biomedical Engineering, Biochemistry, Biotechnology or related field

  • Candidates must have an expected graduation date after August 2026.

  • Previous research experience (academic or industrial) involving cell culture, molecular biology, or virology is a plus

  • Laboratory skills required differ by project. We

    • Mammalian cell culture
    • Virus neutralization assays
    • Flow cytometry (Including high parameter and analysis)
    • ELISA
    • Biolayer interferometry
    • Aseptic technique
    • Pipetting
    • Reagent Preparation
    • DNA extraction and scRNAseq
  • Experience with data analysis tools such as GraphPad Prism and/or introductory coding or data analysis exposure (e.g., Python, R) is a plus.

  • Understanding of MS Office Suite (Excel, Word, PowerPoint)

  • US Work Authorization is required at time of application.

  • Ability to report onsite to Gaithersburg, MD 5 days per week. This role will not provide relocation assistance.

  • Compensation range: $37 – 48 per hour. Wages are commensurate with education and experience.